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Zennara Aesthetics & Wellness
Skin booster injection on the neck at Zennara Clinic, Hyderabad
Bio-Remodeling Injectable

Profhilo in Hyderabad

Gold standard bio-remodeling treatment. Ultra-pure hybrid hyaluronic acid. Highest HA concentration without crosslinking. Deep hydration plus skin tightening. BAP injection technique. Natural 360-degree rejuvenation.

Session
10–15 minutes
Downtime
1 day of small bumps
Discomfort
Minimal
Sessions
2, four weeks apart
Results
4–8 weeks
Lasts
6–9 months

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4.8
676 Google reviews
25,000+
Happy clients
3
Industry awards
M.D.
Dermatologist-led
Since 2019
Trusted by celebrities
In short

Profhilo at a glance

Profhilo is an injectable skin booster made of highly concentrated hyaluronic acid. It is injected at just 10 points and spreads under the skin to hydrate and firm it, building four types of collagen. It is not a filler, so your features do not change. Two sessions four weeks apart give results that last 6–9 months.

Overview

What is Profhilo?

Profhilo is a revolutionary bio-remodeling injectable treatment containing the highest concentration of ultra-pure hybrid hyaluronic acid (64mg/2ml) without any crosslinking agents. Unlike traditional dermal fillers that add volume and structure or conventional skin boosters that simply hydrate, Profhilo works through patented NAHYCO (Highest Molecular Weight) technology—creating a unique slow-releasing hybrid cooperative complex of high and low molecular weight HA that spreads beautifully throughout tissue triggering profound bio-remodeling effects.

Injected at 10 specific BAP (Bio Aesthetic Points)—5 on each side of the face—Profhilo disperses naturally over 2-4 hours creating a uniform blanket of hydration while simultaneously stimulating four types of collagen (I, III, IV, VII) and elastin production. This dual action—immediate deep hydration plus long-term structural improvement—delivers comprehensive skin quality transformation: increased thickness, improved elasticity, reduced laxity, enhanced radiance, refined texture. Not a filler, not just a booster—Profhilo is true bio-remodeling creating 360-degree lifting and tightening effect through tissue reorganization. The treatment protocol involves 2 sessions spaced 4 weeks apart, with results developing progressively over 8-12 weeks and lasting 6-9 months. Ideal for facial laxity, dehydrated skin, crepey neck, aging hands, preventive maintenance.

Profhilo at Zennara is the ultimate bio-remodeling treatment for comprehensive skin quality transformation. Experience the gold standard in injectable hydration and tightening.

Why it works

Benefits of Profhilo

01

Bio-remodeling for complete skin transformation

02

Benefits of Profhilo

03

Ultra-Deep Hydration

04

64mg/2ml highest HA concentration

05

Bio-Remodeling

06

Collagen & elastin stimulation

07

Skin Tightening

08

360-degree lifting effect

09

Natural Radiance

10

Luminous healthy glow

11

Minimal Injections

12

Only 10 BAP points total

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How it works

Gold standard bio-remodeling treatment. Ultra-pure hybrid hyaluronic acid. Highest HA concentration without crosslinking. Deep hydration plus skin tightening. BAP injection technique. Natural 360-degree rejuvenation.

Profhilo—ultra-pure hybrid hyaluronic acid, highest HA concentration, patented NAHYCO technology. Deep hydration plus skin tightening. BAP technique, 10 points only. 360-degree quality transformation. Schedule consultation today.

Your treatment

Profhilo, step by step

  1. Profhilo skin booster syringe at Zennara Clinic, Hyderabad
    1

    Profhilo: pure hyaluronic acid that hydrates from within

  2. Skin booster injection on the neck at Zennara Clinic, Hyderabad
    2

    A few small injection points on the face or neck

  3. Client with glowing skin after skin rejuvenation at Zennara Clinic, Hyderabad
    3

    Firmer, more radiant skin over the following weeks

Is it right for you?

Who Profhilo suits

Your dermatologist confirms this at the consultation, after looking at your skin and history.

A good choice if you have

  • Dehydrated, crepey or lax skin
  • Fine lines on the face, neck or hands
  • Early loss of firmness

Not suitable, or speak to us first

  • Pregnancy or breastfeeding
  • Active infection, cold sores or acne in the area
  • Blood thinners or a bleeding disorder: speak to us first
  • Known allergy to the product or its ingredients
Safety & recovery

Profhilo: side effects and recovery

What you may notice afterwards, how we take care of it, and what each day looks like.

Possible side effect How we manage it
Small bumps or redness at injection pointsFade within hours to a day
BruisingIce and arnica; covered with makeup after 24 hours, fades within a week
Mild tenderness or swellingSettles in 1–3 days; paracetamol if needed
  1. Day 1

    Avoid makeup, workouts, saunas and alcohol; no pressing or massaging the area

  2. Day 2–3

    Small bumps or bruises fade; normal routine

  3. Week 2

    Final look settles; review appointment if advised

Your doctors

Dermatologists who perform Profhilo

Choose your doctor when you book. Every treatment is doctor-led, never delegated.

Good to know

Frequently asked questions on Profhilo

How is Profhilo different from other skin boosters?+

Profhilo stands apart through unique formulation and mechanism: Unique NAHYCO technology: Patented thermal process creates hybrid cooperative complex of high + low molecular weight HA. No crosslinking agents—completely pure hyaluronic acid. Highest concentration: 64mg/2ml—more than any other injectable HA product. Other boosters typically 20mg/2ml. Ultra-pure formulation: No additives, stabilizers, or chemicals. Just pure bio-fermented HA. How this translates to superior results: Spreads more extensively (2-4cm from each injection point vs. staying localized). Triggers stronger bio-remodeling response—stimulates 4 types of collagen + elastin. Dual mechanism: immediate hydration PLUS structural improvement. Longer duration: 6-9 months vs. other boosters 4-6 months. More comprehensive effect: true 360-degree skin quality transformation. BAP technique: Revolutionary injection protocol—only 10 points for entire face. Other boosters require 20-50+ injections same area. Minimizes discomfort, maximizes results. Clinical evidence: Extensive published studies demonstrating superior efficacy. Gold standard bio-remodeling treatment worldwide. Comparison to specific products: vs. Juvederm Volite: Profhilo spreads more, stronger bio-remodeling. vs. Restylane Vital: Higher HA concentration, better tightening effect. vs. Teosyal Redensity: More comprehensive quality improvement. Profhilo essentially created the “bio-remodeling” category—other products are skin boosters, Profhilo goes beyond to actual tissue reorganization and rejuvenation.

Does Profhilo hurt?+

Minimal discomfort—most patients tolerate very well: During injection: Only 10 BAP points total (5 each side). Quick succession—entire procedure 5-10 minutes. Fine needle, smooth product flow. Brief pinprick sensation each injection. Pain level: Most describe 2-3 on 10-point scale. More tolerable than traditional fillers (fewer injections, thinner product). Comparable to or easier than Anti-wrinkle. Numbing: Optional topical cream available (rarely needed). Most patients comfortable without numbing. Ice pack pre/post-treatment reduces any discomfort. Post-injection: Visible papules (bumps) at injection sites but not painful. Just noticeable cosmetically for 24-48 hours. Mild tenderness if touched first day. No significant ongoing pain. Factors affecting comfort: Injector technique (experienced practitioners minimize discomfort). Product temperature (room temp Profhilo more comfortable than cold). Patient anxiety (relaxation helps—most surprised how easy it is). Comparison to other treatments: Less uncomfortable than: Filler injections (more product, deeper placement). Microneedling (hundreds of needle penetrations). Laser treatments (heat discomfort). More uncomfortable than: Topical skincare (obviously). Comparable to: Skin boosters, Anti-wrinkle (brief tolerable discomfort). Overall: Brief mild discomfort for 6-9 months of beautiful bio-remodeled skin. Worthwhile trade-off for vast majority. The visible papules post-treatment more cosmetically concerning than painful—plan timing accordingly.

How long do Profhilo results last?+

Duration 6-9 months typically with proper maintenance: Results timeline: Weeks 1-4: Initial hydration glow developing. Session 2 (Week 4): Second treatment amplifies effect. Weeks 5-12: Progressive bio-remodeling, peak results 8-12 weeks post-final session. Months 4-9: Beautiful maintained results, gradual decline begins month 6+. Why relatively long-lasting: Actual collagen and elastin production (not just temporary hydration). New structural proteins persist months after HA absorbed. Tissue reorganization creates lasting improvement. Cumulative benefits with repeated treatments. Factors affecting duration: Age (younger skin maintains longer). Baseline skin quality (healthier = better retention). Lifestyle (smoking, sun damage accelerate breakdown). Number of sessions (standard 2-session protocol optimal). Skincare compliance (quality products, sun protection extend results). Maintenance protocol: Initial series: 2 sessions 4 weeks apart. Maintenance: Single session every 6-9 months. Annual protocol common: 2 treatments yearly (spring/fall). Some patients quarterly if severe aging or prevention-focused. Comparison to other treatments: Longer than: Conventional skin boosters (4-6 months), Anti-wrinkle (3-4 months). Comparable to: Premium fillers (6-12 months depending on area). Shorter than: Thread lift (12-18 months), surgical procedures (years). Cumulative improvement: Regular Profhilo creates progressive skin quality enhancement. Each treatment builds upon previous—skin gets better and better. Long-term maintenance preserves youthful quality indefinitely. Cost perspective: ₹25,000-35,000 per session. Annual maintenance ₹50,000-70,000 (2 sessions). Investment in skin health comparable to quality skincare but far more effective. Think preventive maintenance delaying need for more invasive procedures later.

What's the downtime after Profhilo?+

Minimal downtime but visible papules first 24-48 hours: Immediate post-treatment: 10 visible papules (bumps) at BAP injection sites. Each papule small (pea-sized), raised, may be slightly red. Not painful, just cosmetically visible. Cannot cover effectively with makeup immediately. Days 1-2: Papules gradually flattening as Profhilo spreads through tissue. Most patients: papules resolve 24-48 hours. Some (thicker skin): may persist 48-72 hours. Possible mild swelling around eyes if face treated (rare, resolves day 2-3). Day 3+: All visible effects typically resolved. Skin looks hydrated, glowing. Social downtime: Most patients prefer 48 hours “papule time” before important events. Can go to work day 2-3 usually (papules smaller but may be visible). Plan 3-5 days before major occasions for complete resolution. Activity restrictions: No makeup 4-6 hours. No exercise 24 hours. No extreme heat (sauna, hot yoga) 48 hours. No facial massage/treatments 1 week. Gentle cleansing only first 24 hours. Sleep elevated first night (optional but helps). Bruising: Uncommon but possible (10-15% of patients). Small purple marks at injection sites if occurs. Fade within week. Arnica supplements minimize risk. Comparison: More visible effects immediately than: Anti-wrinkle (tiny marks only), fillers (swelling but no distinct papules). Less downtime than: Microneedling (redness 3-5 days), lasers (redness 5-10 days), peels (peeling 5-7 days). Planning tips: Schedule 5-7 days before important events. Friday afternoon treatment = ready by Tuesday typically. Avoid right before weddings, photo shoots, presentations. Overall: Manageable short-term visibility for long-lasting skin quality transformation. The papules are hallmark of proper Profhilo technique—indicate correct BAP placement and dose.

Can Profhilo be combined with other treatments?+

Yes—excellent synergistic combinations for comprehensive rejuvenation: Highly complementary pairings: Anti-wrinkle: Profhilo improves skin quality, Anti-wrinkle relaxes wrinkles. Different mechanisms, combined effect powerful. Can do same day or space 2-4 weeks. Dermal Fillers: Profhilo creates healthy skin canvas, fillers restore volume/contour. Perfect combination addressing quality + structure. Usually space 2-4 weeks allowing each to settle independently. Lasers: Profhilo enhances skin before laser (better healing capacity). Or after laser (accelerates recovery, enhances results). Space 2-4 weeks minimum. Microneedling: Both stimulate collagen—synergistic bio-remodeling. Space 4-6 weeks. Can do Profhilo post-microneedling for enhanced penetration (advanced technique). Chemical Peels: Peels for surface renewal, Profhilo for deep quality. Complementary depths. Space 2-4 weeks. Skincare: Essential! Profhilo regenerates internally, quality products maintain externally. Medical-grade vitamin C, retinoids, growth factors, peptides. Daily SPF 50+ critical protecting investment. Timing strategy: Don’t overload face with multiple procedures same day unless specifically designed protocol. Plan comprehensive approach over 2-3 months. Profhilo often foundation—establish quality then add targeted treatments. What works well simultaneously: Profhilo + Anti-wrinkle same appointment (different mechanisms, no interaction). Profhilo one area + filler another area (face vs. lips for example). What to space apart: Profhilo + aggressive laser (both cause inflammation—space adequately). Multiple bio-stimulators close together (allow skin recovery between). Comprehensive protocols: Initial phase (Months 1-3): Profhilo sessions 1 & 2 (weeks 0 and 4), Anti-wrinkle (week 6), fillers if needed (week 8-10). Maintenance phase: Profhilo every 6-9 months, Anti-wrinkle every 3-4 months, fillers as needed. Our approach: Customized multi-modal treatment plans. Profhilo cornerstone of quality-focused protocols. Strategic combinations deliver most natural complete transformation.

How much does Profhilo cost?+

Premium pricing reflecting unique formulation and efficacy: Per session cost: Face: ₹25,000-35,000 per vial (2ml). Neck: ₹25,000-35,000 per vial. Face + Neck: ₹50,000-70,000 (2 vials). Hands: ₹20,000-30,000 per vial. Décolletage: ₹25,000-35,000 per vial. Standard protocol cost: Initial series (2 sessions face): ₹50,000-70,000 total. Initial series (2 sessions face + neck): ₹1,00,000-1,40,000 total. Maintenance (annual): Single session every 6-9 months: ₹25,000-35,000 face. Two sessions yearly: ₹50,000-70,000 face. Why premium priced: Patented NAHYCO technology (proprietary formulation). Highest HA concentration available (64mg/2ml). Pharmaceutical-grade manufacturing (IBSA Swiss quality). Extensive clinical research and development. Superior efficacy and duration. Global gold standard reputation. Factors affecting price: Practitioner expertise (experienced injectors charge premium). Geographic location (metro cities higher). Clinic reputation. Product authenticity guarantee (only from authorized distributors). Number of areas treated (more zones = more vials). Comparison to alternatives: More expensive than: Conventional skin boosters (₹15,000-25,000), PRP (₹8,000-15,000). Comparable to: Premium skin boosters (Juvederm Volite, Restylane Vital similar range). Less expensive than: Multiple filler syringes (₹25,000-45,000 each, often need 2-4), thread lift (₹1,20,000-2,50,000), laser series (₹60,000-1,50,000). Value proposition: Most effective bio-remodeling treatment available. Addresses skin quality comprehensively (hydration + tightening + collagen). Long-lasting results (6-9 months). Minimal injections (only 10 BAP points). Annual maintenance investment (₹50,000-70,000) for sustained quality. Red flags: Too cheap (₹15,000-18,000): Likely counterfeit, expired, or over-diluted product. Dangerous—unknown contents, contamination risk, ineffective or harmful. Package deals with pressure: Avoid. Pay per treatment as needed based on individual response. Non-medical settings: Profhilo should only be administered by trained medical professionals. Our pricing: Transparent, competitive reflecting authentic product and expertise. No hidden fees. Worth investment for transformative bio-remodeling from gold standard treatment.

Is Profhilo safe?+

Excellent safety profile—one of safest aesthetic injectables: Why very safe: Pure hyaluronic acid—naturally occurring substance in body. No crosslinking agents, additives, or chemicals. Bio-fermented, pharmaceutical-grade production. Extensive clinical studies demonstrating safety. Used globally for years, millions of treatments. Superficial injection depth (minimal risk to deeper structures). Fully reversible (hyaluronidase dissolves HA if needed—extremely rare). Common effects (normal, temporary): Visible papules: Expected at 10 BAP points, resolve 24-48 hours. Mild swelling: Especially around eyes, resolves 2-3 days. Slight redness: At injection sites, fades within hours. Tenderness: First 24 hours if area touched. All completely normal healing responses. Rare complications: Bruising: 10-15% patients, small purple marks fade within week. Prolonged papules: Occasionally persist 3-4 days (thicker skin). Asymmetry: Very rare with proper BAP technique, correctable. Infection: Extremely rare with sterile technique. Granulomas: Exceptionally rare inflammatory nodules, treatable. Very rare serious events: Vascular occlusion: Theoretical risk any injectable, extremely rare with Profhilo (superficial placement). Allergic reaction: Almost unheard of (pure HA, no additives). No systemic effects documented. Contraindications: Pregnancy/breastfeeding (precautionary). Active infection/inflammation at treatment site. Autoimmune conditions affecting skin (individual assessment). Allergy to HA (extremely rare). Previous allergic reaction to HA fillers. Safety vs. other treatments: Safer than: Surgical procedures (no anesthesia, incisions). Permanent fillers (Profhilo fully absorbable). Comparable to: Other HA skin boosters, dermal fillers (similar safety profiles). Our protocols: Only authentic Profhilo from authorized distributors. Board-certified medical practitioners only. Sterile technique, medical-grade facility. Comprehensive screening and consent. Post-treatment monitoring. Emergency medications available. Overall: Among safest aesthetic treatments available. Risk-benefit ratio excellent for patients seeking skin quality improvement.

Who should get Profhilo?+

Ideal for specific concerns and life stages: Perfect candidates: Age 30s-50s: Sweet spot for Profhilo. Early to moderate aging visible. Skin still responsive to bio-remodeling. Preventive plus corrective benefits. Dehydrated skin: Profhilo’s forte—deep multilayer hydration. Dull, tired-looking complexion. Rough crepey texture. Loss of radiance. Early laxity: Mild skin loosening, loss of bounce. Jawline softening, jowl formation beginning. Neck showing crepiness. Not severe sagging (need threads/surgery for that). Specific concerns: Neck and décolletage aging (exceptional results). Aging hands (restores plump youthful appearance). Preventive maintenance (30s-40s preserving quality). Post-weight loss (improves skin retraction). Lifestyle factors: Smokers (skin damage repair). Sun damage (reverses some effects). Stress/poor sleep (revitalizes tired skin). Not ideal for: Severe sagging/excess skin: Profhilo improves quality but won’t dramatically lift severe laxity. Need threads, surgery, or combination approach. Very young patients (<25): Unnecessary—skin still naturally optimal. Unless specific concerns like severe dehydration from medical conditions. Those seeking volume: Profhilo doesn’t add fullness to lips, cheeks. Need fillers for volume restoration. Unrealistic expectations: Profhilo amazing for quality, not dramatic transformation overnight. Budget constraints: Requires 2-session commitment plus maintenance. Investment needed for sustained results. Age considerations: 20s: Rarely needed unless specific damage. 30s-40s: Prevention plus early correction. Ideal candidates. 50s-60s: Still beneficial but may need combination approach (Profhilo + fillers + Anti-wrinkle). 70s+: Can help but realistic expectations crucial. May need more invasive options for dramatic improvement. Consultation determines: Individual skin assessment. Realistic expectation setting. Whether Profhilo alone sufficient or combination needed. Customized protocol for your specific concerns and goals.

From our blog

Read more about Profhilo

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Credentials

Why clients trust Zennara

M.D. Dermatologists

Every treatment led by qualified, registered doctors

FDA-approved technology

Lasers and devices from globally certified makers

Sterile protocols

Single-use consumables and medical-grade hygiene

Written treatment plan

Sessions, timeline and price agreed before you start

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No photos or records shared without written consent

Award-winning clinic

Recognised at the Forttuna Global Excellence Awards

Doctor’s tips

Skin & hair advice from our dermatologists

Short, honest tips every week. Follow along on Instagram.

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Find us

Profhilo near you

Three private clinics across Hyderabad. Choose one to see the map, today’s hours and directions.

Private consultation

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Tell us when suits you. A senior dermatologist will see you in a private room, explain your plan and share exact pricing. No pressure, no waiting room.

  • No-obligation consultation. You decide after you see your plan.
  • A senior dermatologist sees you, not a sales counsellor.
  • Call back within minutes during clinic hours.
  • Your details stay private and are never shared.
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